Microbiomics of ocean organism for new natural products

We contributed an NMR analysis to a major research effort of the Sunagawa and Piel laboratories. In this work, the genomes of countless ocean microorganisms were mined and thereby the number of know genomic sequences was increased 2–3 fold. Tens of thousands of gene clusters were identified with predicted novel synthetic capabilities. Some of them were reproduced experimentally and the resulting products were confirmed by NMR.