Models for cell-permeability from eNOEs
Sampling the conformational space of modified macrocyclic peptides by eNOES: models for cell permeability
Together with the group of Prof. Künzler and Prof. Güntert we propose a model for cell-permeation of modified macrocyclic peptides. The model is based on NMR structures which were obtained using a novel eNOE approach in various solvent mixtures. The solvent mixtures mimic various cellular compartments.